Solve Mixture Problems: Combining Two Solutions

Medication Dosage 9th-10th Grade
Problem
A veterinarian needs a mixture containing 10% of a certain medication to treat an injured bird. How many milliliters of a 16% solution should be mixed with 6 ml of a 5% solution to obtain a solution that is 10% medication?

What This Problem Teaches

  • Setting up equations based on the conservation of pure medication
  • Converting percentages to decimals for calculations
  • Understanding that mixing solutions requires balancing substance amounts, not just volumes
  • Solving linear equations with practical constraints (volumes must be positive)
  • Verifying solutions by checking final concentrations make physical sense

Visualizing the Problem

Let's create a clear picture of what we're mixing:

A veterinarian needs a mixture containing 10% of a certain medication to treat an injured bird. How many milliliters...
SolutionVolume (ml)ConcentrationPure Medication (ml)
Strong solutionx16%0.16x
Weak solution65%6 × 0.05 = 0.30
Final mixturex + 610%0.10(x + 6)

Solution: Method 1 — Medication Mass Balance

The key insight is that pure medication is conserved when we mix solutions. The total amount of medication before mixing equals the total amount after mixing.

Step 1 — Define the variable

Let x = milliliters of 16% solution needed.

Step 2 — Calculate pure medication in each component

Pure medication is found by multiplying volume by concentration:

  • From 16% solution: x × 0.16 = 0.16x ml of medication
  • From 5% solution: 6 × 0.05 = 0.30 ml of medication
  • In final mixture: (x + 6) × 0.10 = 0.10(x + 6) ml of medication

Step 3 — Set up the medication balance equation

The medication from both original solutions equals the medication in the final mixture:

Medication from 16% + Medication from 5% = Medication in final mixture
0.16x + 0.30 = 0.10(x + 6)

Step 4 — Solve the equation

Expand the right side and collect like terms:

0.16x + 0.30 = 0.10x + 0.60
0.16x - 0.10x = 0.60 - 0.30
0.06x = 0.30
x = 0.30 ÷ 0.06 = 5

Step 5 — State the complete answer

The veterinarian needs 5 ml of the 16% solution.

Solution: Method 2 — The Concentration Difference Approach

This method uses the concept that we're moving the 5% solution "up" to 10%, while the 16% solution gets "diluted down" to 10%.

Step 1 — Calculate concentration differences

Find how far each solution is from the target concentration:

  • 5% solution needs to increase by: 10% - 5% = 5%
  • 16% solution will decrease by: 16% - 10% = 6%

Step 2 — Set up the ratio

The volume ratio should be inversely related to the concentration differences:

Volume of 16% solution : Volume of 5% solution = 5 : 6
x : 6 = 5 : 6

Step 3 — Solve the proportion

x/6 = 5/6
x = 6 × 5/6 = 5

This confirms our answer: 5 ml of the 16% solution.

Answer: 5 milliliters of the 16% solution should be mixed with the 6 ml of 5% solution.

Verification

Let's check our answer by calculating the final concentration:

Calculate total medication

  • From 5 ml of 16% solution: 5 × 0.16 = 0.80 ml
  • From 6 ml of 5% solution: 6 × 0.05 = 0.30 ml
  • Total medication: 0.80 + 0.30 = 1.10 ml

Calculate total volume and final concentration

  • Total volume: 5 + 6 = 11 ml
  • Final concentration: 1.10 ÷ 11 = 0.10 = 10% ✓

Perfect! Our answer gives exactly the required 10% concentration.

Common Pitfalls

✗ Mistake 1: Setting up the equation as 0.16x + 0.05(6) = 0.10(x)
Why it's wrong: This ignores the volume contribution of the 5% solution to the final mixture. The final volume is x + 6, not just x.
✗ Mistake 2: Using percentages directly: 16x + 5(6) = 10(x + 6)
Why it's wrong: You must convert percentages to decimals when calculating amounts. This equation inflates all values by a factor of 100.
✗ Mistake 3: Averaging the concentrations: (16% + 5%) ÷ 2 = 10.5%
Why it's wrong: This assumes equal volumes, but we have 6 ml of one solution and an unknown amount of the other. Concentrations must be weighted by volume.
Clinical Note: In veterinary practice, medication concentration errors can be dangerous. Always double-check calculations and verify that the final concentration matches the prescription exactly.

Does This Seem Reasonable?

Let's do a sanity check on our answer of 5 ml:

  • Volume check: We're adding 5 ml of strong solution to 6 ml of weak solution. Since 5 < 6, we expect the final concentration to be closer to the weak solution, which it is (10% is closer to 5% than to 16%).
  • Concentration logic: The 16% solution is 6 percentage points above our target, while the 5% solution is 5 points below. We need slightly less of the stronger solution, which matches our 5:6 ratio.
  • Practical context: For treating a small bird, 11 ml total volume (5 + 6) is a reasonable amount for a veterinarian to work with.

The answer passes all reasonableness tests.

The Pattern Behind This

All mixture problems follow the same fundamental principle: the amount of pure substance is conserved.

General Mixture Formula:

C₁V₁ + C₂V₂ = C_final(V₁ + V₂)

Where:
• C₁, C₂ = concentrations of original solutions
• V₁, V₂ = volumes of original solutions
• C_final = desired final concentration

This same structure applies whether you're mixing:

  • Medication solutions (like this problem)
  • Salt water of different concentrations
  • Alcohol solutions for chemistry
  • Fertilizer mixtures for agriculture

The key is identifying what substance is being conserved (medication, salt, alcohol, etc.) and setting up the balance equation correctly.

Why This Matters

Mixture calculations appear throughout healthcare and science:

  • Pharmacy: Compounding custom medication strengths for patients with specific needs
  • Veterinary medicine: Adjusting medication concentrations for different animal sizes and species
  • Laboratory work: Preparing reagent solutions with precise concentrations for experiments
  • Food industry: Creating products with specific nutrient or additive concentrations

In clinical settings, these calculations are often double-checked by multiple professionals because concentration errors can have serious consequences for patient safety.

What If?

1
Change the Target
The veterinarian needs a 12% medication solution instead. How many milliliters of the 16% solution should be mixed with 6 ml of the 5% solution?
Step 1 — Set up the equation

Let x = ml of 16% solution. The medication balance equation becomes: 0.16x + 0.05(6) = 0.12(x + 6)

Step 2 — Simplify

0.16x + 0.30 = 0.12x + 0.72

Step 3 — Solve for x

0.16x - 0.12x = 0.72 - 0.30
0.04x = 0.42
x = 10.5

Step 4 — Verify

Total medication: 10.5(0.16) + 6(0.05) = 1.68 + 0.30 = 1.98 ml
Total volume: 10.5 + 6 = 16.5 ml
Final concentration: 1.98 ÷ 16.5 = 0.12 = 12% ✓

Answer: 10.5 ml of the 16% solution

2
Fixed Final Volume
The vet needs exactly 15 ml of 10% solution. How many ml each of the 16% and 5% solutions should be mixed?
Step 1 — Set up variables

Let x = ml of 16% solution and y = ml of 5% solution.
We know: x + y = 15 (total volume constraint)

Step 2 — Medication equation

0.16x + 0.05y = 0.10(15) = 1.5

Step 3 — Substitute and solve

From volume equation: y = 15 - x
Substitute: 0.16x + 0.05(15 - x) = 1.5
0.16x + 0.75 - 0.05x = 1.5
0.11x = 0.75
x = 6.82 ml

Step 4 — Find y

y = 15 - 6.82 = 8.18 ml

Answer: Mix 6.82 ml of 16% solution with 8.18 ml of 5% solution

3
Reverse the Unknown
The vet has 8 ml of the 16% solution. How many ml of the 5% solution must be mixed with it to obtain a 10% solution?
Step 1 — Define variable

Let y = ml of 5% solution needed

Step 2 — Set up equation

Medication from 16% + Medication from 5% = Medication in final mixture
0.16(8) + 0.05y = 0.10(8 + y)

Step 3 — Solve

1.28 + 0.05y = 0.80 + 0.10y
1.28 - 0.80 = 0.10y - 0.05y
0.48 = 0.05y
y = 9.6

Step 4 — Verify

Total medication: 1.28 + 0.05(9.6) = 1.28 + 0.48 = 1.76 ml
Total volume: 8 + 9.6 = 17.6 ml
Final concentration: 1.76 ÷ 17.6 = 0.10 = 10% ✓

Answer: 9.6 ml of the 5% solution

4
Three-Component Mix
The vet has 16%, 5%, and pure water (0%) solutions. She uses 4 ml of the 5% solution and 3 ml of pure water. How much 16% solution is needed to make the final mixture 8% medication?
Step 1 — Set up the problem

Let x = ml of 16% solution needed
Components: x ml of 16%, 4 ml of 5%, 3 ml of 0%

Step 2 — Calculate medication from each

From 16%: 0.16x ml
From 5%: 4 × 0.05 = 0.20 ml
From water: 3 × 0 = 0 ml

Step 3 — Set up equation

Total medication = Final concentration × Total volume
0.16x + 0.20 + 0 = 0.08(x + 4 + 3)
0.16x + 0.20 = 0.08(x + 7)

Step 4 — Solve

0.16x + 0.20 = 0.08x + 0.56
0.16x - 0.08x = 0.56 - 0.20
0.08x = 0.36
x = 4.5

Step 5 — Verify

Total medication: 4.5(0.16) + 0.20 = 0.72 + 0.20 = 0.92 ml
Total volume: 4.5 + 4 + 3 = 11.5 ml
Final concentration: 0.92 ÷ 11.5 = 0.08 = 8% ✓

Answer: 4.5 ml of the 16% solution

Frequently Asked Questions

How do you calculate how much medication is in a percentage solution?+
Multiply the volume by the percentage concentration. For example, 6 ml of a 5% solution contains 6 × 0.05 = 0.3 ml of pure medication. This amount of medication stays constant when you mix solutions.
Why do you set up an equation based on medication amounts rather than volumes?+
Because medication doesn't disappear when you mix - it's conserved. In this problem, 0.16x ml from the strong solution plus 0.3 ml from the weak solution must equal the total medication in the final mixture. Volume mixing follows different rules.
How do you check if your mixture calculation is correct?+
Calculate the total medication and total volume separately, then verify the concentration. Here, with 5 ml of 16% solution: (5 × 0.16) + (6 × 0.05) = 0.8 + 0.3 = 1.1 ml total medication. Final concentration: 1.1 ÷ 11 = 0.10 = 10% ✓
NJ
Neven Jurkovic, PhD

Professor of Computer Science, Palo Alto College, Alamo Colleges District, San Antonio, TX

Developer of Algebrator

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This solution was prepared with AI assistance and reviewed by Dr. Jurkovic for mathematical accuracy and pedagogical clarity.

2026-10-30