Solve Medication Dosage Using Proportions

Medication Dosage 7th-8th Grade
PROBLEM
As a nurse, you mix Medication A with Medication B in the same proportion for your patients. Last week you mixed 90 milligrams of Medication A with 36 milligrams of Medication B. This week, the doctor said to use only 12 milligrams of Medication B. How many milligrams of Medication A should be mixed this week?

What This Problem Teaches

  • Setting up and solving proportions with real-world applications
  • Understanding the critical importance of maintaining exact medication ratios
  • Converting between different quantities while preserving relationships
  • Cross-multiplication as a tool for solving proportional equations
  • Verification techniques to ensure dosing accuracy in healthcare settings

Solution: Method 1 — The Proportion Setup

The key insight here is recognizing that "same proportion" means the ratio of Medication A to Medication B must remain constant. Let's set up a proportion comparing last week's mixture to this week's.

Step 1 — Identify the known ratio

From last week's mixture, we know the ratio of Medication A to Medication B:

Ratio = 90 mg A : 36 mg B

Step 2 — Set up the proportion

We can write this as a proportion where x represents the unknown amount of Medication A needed this week:

90 mg A / 36 mg B = x mg A / 12 mg B

Step 3 — Cross-multiply

Cross-multiplication gives us:

90 × 12 = 36 × x
1080 = 36x

Step 4 — Solve for x

Divide both sides by 36:

x = 1080 ÷ 36 = 30
30 milligrams of Medication A should be mixed this week.

Solution: Method 2 — The Scaling Factor Approach

Another way to think about this problem is to find how much the medication amounts have been scaled down, then apply that same scaling factor to both medications.

Step 1 — Find the scaling factor

Compare this week's Medication B to last week's:

Scaling factor = 12 mg ÷ 36 mg = 1/3

Step 2 — Apply the scaling factor to Medication A

Since we're using 1/3 as much Medication B, we need 1/3 as much Medication A:

Medication A needed = 90 mg × (1/3) = 30 mg

Step 3 — Verify the ratios match

Let's check that both mixtures have the same ratio:

Last week: 90:36 = 5:2
This week: 30:12 = 5:2 ✓
30 milligrams of Medication A should be mixed this week.

Verification

Let's verify our answer by checking that both medication mixtures have identical ratios:

Last week's ratio: 90 mg A ÷ 36 mg B = 2.5
This week's ratio: 30 mg A ÷ 12 mg B = 2.5 ✓

We can also verify by substituting back into our original proportion:

90/36 = 30/12
2.5 = 2.5 ✓

Both checks confirm our answer is correct.

Why Precision Matters in Healthcare

Critical Safety Note: In real clinical practice, medication ratios must be maintained exactly as prescribed. Even small deviations can affect therapeutic effectiveness or cause adverse reactions. Always double-check calculations and have another healthcare professional verify dosing when possible.

This problem demonstrates why healthcare professionals must be meticulous with proportional calculations. The 5:2 ratio (Medication A to Medication B) represents a specific therapeutic balance that the prescribing physician determined was optimal for patient care.

Watch Out For These

Medication dosing errors can have serious consequences. Here are the most common mistakes in proportion problems:

✗ Mixing up the ratios

Setting up: 36/90 = 12/x (putting B/A instead of A/B consistently)

This leads to x = 3.6 mg, which would create a dangerously weak mixture. Always keep the same medication in the same position (numerator or denominator) on both sides.

✗ Unit confusion

Confusing milligrams (mg) with micrograms (mcg) or other units

In healthcare, mg and mcg differ by a factor of 1000. Always verify units match before calculating. When in doubt, convert everything to the same unit first.

✗ Forgetting to verify

Accepting an answer without checking that ratios are actually equal

Always calculate both ratios as decimals to confirm they match. In this problem, both ratios should equal 2.5.

How to Spot This Problem Type

Look for these key phrases that signal a proportion problem:

  • "Same proportion" or "same ratio" — the most direct signal
  • "Mix A with B" followed by specific amounts — suggests a recipe or formula
  • Two scenarios with some amounts given and others missing — classic proportion setup
  • Healthcare or pharmacy context — these frequently involve proportional dosing

NCLEX Connection: Nursing students will see similar problems on the NCLEX exam, often disguised as "concentration" or "solution strength" problems. The mathematical structure is identical — find the ratio from known information, then scale proportionally.

The Pattern Behind This

This is a direct proportion problem, which follows the general pattern:

If A₁/B₁ = A₂/B₂, then A₂ = (A₁ × B₂)/B₁

In our medication context:

  • A₁ = original amount of Medication A (90 mg)
  • B₁ = original amount of Medication B (36 mg)
  • B₂ = new amount of Medication B (12 mg)
  • A₂ = new amount of Medication A (what we're solving for)

This formula works whenever you need to maintain a constant ratio between two quantities. The limitation is that it only works for direct relationships — if one amount increases, the other increases proportionally.

Where This Shows Up Beyond Textbooks

  • Pharmacy compounding: Creating custom medication mixtures with precise active ingredient ratios
  • IV drip calculations: Scaling medication concentrations based on patient weight or condition severity
  • Cooking and baking: Scaling recipes up or down while maintaining flavor balance
  • Manufacturing: Maintaining alloy compositions when producing different batch sizes
  • Chemistry labs: Preparing solutions with specific molar ratios of reactants

Try These Variations

1
Reverse the Question
As a nurse, you mix Medication A with Medication B in the same proportion. Last week you mixed 90 mg of A with 36 mg of B. This week, the doctor says to use 75 mg of Medication A. How many milligrams of Medication B should be mixed this week?
Step 1 — Set up the proportion

We know the ratio from last week and this week's amount of A: 90 mg A / 36 mg B = 75 mg A / x mg B

Step 2 — Cross-multiply

90 × x = 36 × 75
90x = 2700

Step 3 — Solve for x

x = 2700 ÷ 90 = 30

Step 4 — Verify

Check ratios: 90/36 = 2.5 and 75/30 = 2.5 ✓

Answer: 30 mg of Medication B

2
Different Ratio
As a nurse, you usually mix Medication A with Medication B in a 5:2 ratio. This week, the doctor wants to change the ratio to 3:1 (A:B) for a new patient. You have 15 mg of Medication B. How many mg of A should you use with the new ratio?
Step 1 — Understand the new ratio

The new ratio is 3:1, meaning 3 parts A for every 1 part B

Step 2 — Set up the proportion

3 parts A / 1 part B = x mg A / 15 mg B

Step 3 — Cross-multiply

3 × 15 = 1 × x
45 = x

Step 4 — Verify

Check ratio: 45/15 = 3, which matches the 3:1 ratio ✓

Answer: 45 mg of Medication A

3
Total Dose Target
As a nurse, you mix Medication A with Medication B in a 5:2 ratio. The doctor needs a total mixture of 105 mg (A + B combined). How many mg of each medication do you need?
Step 1 — Find total ratio parts

Ratio 5:2 means 5 + 2 = 7 total parts

Step 2 — Find value per part

105 mg ÷ 7 parts = 15 mg per part

Step 3 — Calculate each medication

Medication A: 5 parts × 15 mg/part = 75 mg
Medication B: 2 parts × 15 mg/part = 30 mg

Step 4 — Verify

Total: 75 + 30 = 105 mg ✓
Ratio: 75:30 = 5:2 ✓

Answer: 75 mg of A, 30 mg of B

4
Three-Medication Mix
As a nurse, you mix Medications A, B, and C in the ratio 5:2:1. Last week you used 90 mg of A. This week, the doctor says to use only 8 mg of B. How many mg of A and C should you use this week to maintain the same ratio?
Step 1 — Find the scaling factor using B

Last week's B amount: 90 mg A × (2/5) = 36 mg B
Scaling factor: 8 mg ÷ 36 mg = 2/9

Step 2 — Calculate A for this week

90 mg × (2/9) = 20 mg A

Step 3 — Calculate C for this week

Last week's C: 90 mg A × (1/5) = 18 mg C
This week's C: 18 mg × (2/9) = 4 mg C

Step 4 — Verify ratios

This week: 20:8:4 = 5:2:1 ✓

Answer: 20 mg of A, 4 mg of C

Frequently Asked Questions

Write the ratio of medication A to medication B from the known mixture, then set it equal to the ratio using the new amounts. In this problem: 90 mg A / 36 mg B = ? mg A / 12 mg B, then cross-multiply to solve.
Changing the ratio of active ingredients can alter the medication's effectiveness or cause adverse reactions. The therapeutic effect depends on precise ratios. In this example, the 5:2 ratio (90:36 = 5:2) must be maintained for patient safety.
A ratio compares two quantities (like 5:2), while a proportion states that two ratios are equal. Here we use the proportion 90/36 = x/12 to find that x = 30 mg, maintaining the original 5:2 medication ratio.
NJ
Neven Jurkovic, PhD

Professor of Computer Science, Palo Alto College, Alamo Colleges District, San Antonio, TX

Developer of Algebrator

Contact

This solution was prepared with AI assistance and reviewed by Dr. Jurkovic for mathematical accuracy and pedagogical clarity.

2026-11-10